Do you want to become a protein engineering expert? Do you want to set up your own directed evolution campaign? Do you want to computationally analyze enzymes and variants? The AcES² aims to provide unique training and hands-on experience in protein engineering to young researchers. After the successful online AcES-2021 we are really happy to welcome you in Aachen to the educational event for 25 participants who want to learn state-of-the-art computational and wet lab approaches in protein engineering. The training will be provided by the group of Prof. Schwaneberg (RWTH Aachen University) and guest lecturers from several universities and industry. The AcES² is hosted by VFL Biotec. Join interactive summer school to learn and discuss the main concepts, tools, and methods used for protein engineering! Enjoy networking with international researchers, postdocs and PhD students! The AcES² program at a glance General Lectures about Enzyme Discovery and Bioinformatics The Power of Protein Engineering Protein Design Principles High-Throughput Screening Methodologies Smart Library Design Computational Analysis Lectures and Exercises Protein Databases Homology Modeling In silico Analysis AlphaFold CompassR Seminar and Wet-Lab Training Mutagenesis Library Generation Development of Screening Systems Screening of Mutagenesis Library Site Saturation Mutagenesis Understanding Effects of Substitutions Meet the speakers Ulrich Schwaneberg Head of Institute of Biotechnology at RWTH Aachen University & Member of the Scientific Board of Directors of the DWI-Leibniz Institute for Interactive Materials Ulrich Schwaneberg graduated in chemistry (in 1996) and received his PhD (in 1999; supervisor Prof. R. D. Schmid) from the University in Stuttgart. He was, after a postdoc at Caltech in the lab of the Noble laureate Prof. Frances H. Arnold, appointed as Professor at the Jacobs University Bremen in 2002. In January 2009, he moved to the RWTH Aachen University as Head of the Institute of Biotechnology and is since 2010 co-appointed in the Scientific Board of Directors at the DWI Leibniz Institute for Interactive Materials. Furthermore, he coordinates with Prof. Bergs the competence center Bio4MatPro (one of two BMBF flagship projects in the bioeconomy model region), serves in the board of directors in the Bioeconomy Science Center, and is Speaker of the RWTH profile area Molecular Science & Engineering. He is a cofounder of the companies SeSaM Biotech & Aachen Proteineers and has a special interest in Protein engineering to understand fundamental structure-function relationships and provide tailored proteins as building blocks for the biological transformation of material science and production as well as tailored enzymes for bio- and biohybrid-catalysis. In 2016, he received the BMBF-Forschungspreis for the next generation of bioprocesses and has published >350 original manuscripts and is coinventor on >30 patents, mostly with industry. Wolfgang Streit Head of Department of Microbiology and Biotechnology at University of Hamburg D Wolfgang Streit completed his studies in biology at the Philipps University of Marburg in 1989, where he was awarded a doctorate in 1993 for his work on the microbiology of rhizobia. In 1994 he worked as a postdoc at the Philipps University in Marburg and from 1995 to 1997 he worked as a postdoc at the University of California, Davis (USA). From 1997 to 1998 he conducted research at the University of Bielefeld and then headed a working group at the Georg-August-University Göttingen at the Institute for Microbiology and Genetics. From 2004 to 2006 he appointed as a professor for enzyme technology at the University of Duisburg-Essen in the chemistry department. Since 2006, Wolfgang Streit has headed the Department of Microbiology and Biotechnology at the University of Hamburg in the Biology Department as a professor. Wolfgang Streit and his working group focus on metagenomics and the utilization of previously uncultivated microorganisms for biotechnology as well as the identification of new enzymes and valuable biomolecules. These include, for example, lipases, glycosyltransferases and also enzymes for breaking down plastic. On the other hand, the group investigates the molecular processes that lead to the formation of microbial biofilms in order to derive strategies to inhibit biofilm growth. In addition, Wolfgang Streit’s team is interested in bacterial cell-cell communication and biotechnology. Streit is a member of the Association for General and Applied Microbiology, DECHEMA, the American Society for Microbiology and the Hamburg School of Food Science. Björn Usadel Head of Institute for Biological Data Science at the Heinrich-Heine-University Duesseldorf & Head of the Institute for Bioinformatics (IBG-4) at Forschungszentrum Juelich GmbH Björn Usadel (born 1975 in Herdecke) studied biochemistry at the Freie Universität Berlin (diploma 2001). He then moved to the Max Planck Institute for Molecular Plant Physiology in Potsdam, where he did his doctorate in 2005 on the subject of predicting and investigating plant cell wall genes. He also spent his postdoc period in Potsdam, where he most recently headed a junior research group. In 2011, the RWTH Aachen appointed him to a W3 professorship, at the same time he became director of the Institute for Bioinformatics (IBG-4) at the FZJ. Since 2019 he has headed the newly founded Institute for Bioinformatics (IBG-4) at the FZJ. Since April 1st, Dr. Usadel W3 professor at the HHU according to the Berlin model, he continues to head the Jülich IBG-4 and will head the Institute for Biological Data Science in Düsseldorf. Prof. Usadel’s work focuses on bioinformatics. He is particularly interested in methods and algorithms for the evaluation and integration of plant high-dimensional “omics” data. His interests lie in the field of structured data storage of plant data, in the evaluation of new data from genome and transcriptome analysis and in the integration, interpretation and visualization of high-dimensional “omics” data for predicting phenotypes – i.e. the actual shape of a plant, which is encoded in the genome. Participation fees Academia – 900 € | Industry – 1200 € Register If you have any questions, do not hesitate to contact us. Contact